The phthalazine compound, cas is 119-39-1 name is Phthalazin-1(2H)-one, mainly used in chemical industry, its synthesis route is as follows.,119-39-1
2H-phthalazin-1-one (150 mmol), (3,4-dihydroisoquinolin-2(1H)-carboxylic acid tert-butyl ester-5-yl)-carbamic acid o-chlorophenyl ester (195 mmol) were placed in a reaction flask, then DMF100 ml was added and the reaction was carried out at 55 C overnight. The reaction was stopped, added 300 ml of ethyl acetate, 200ml of dichloromethane, and extracted. The organic phase was separated, and the aqueous phase was extracted with dichloromethane (3*50 ml). The organic phase was combined, dried over anhydrous sodium sulfate, and Purification by column chromatography gave the title compound.
As the rapid development of chemical substances, we look forward to future research findings about 119-39-1
Reference£º
Patent; Nanjing Advanced Biological Materials And Process Equipment Institute Co., Ltd.; Guo Chengjie; (16 pag.)CN109336863; (2019); A;,
Phthalazine – Wikipedia
Phthalazine | C8H6N2 – PubChem