Application of 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid

As the rapid development of chemical substances, we look forward to future research findings about 119-39-1

The phthalazine compound, cas is 119-39-1 name is Phthalazin-1(2H)-one, mainly used in chemical industry, its synthesis route is as follows.,119-39-1

[0322] General procedure: To a mixture ofphthalazone in anhydrous DMF (270mL), NaOEt (21% w/w solution in EtOH, 51 mL, 137 mmol) was added. After 15 min,propargyl bromide (80% solution in toluene, 14.8 mL, 20.4 g, 137 mmol) was added and thereaction mixture was stirred at r.t. for 2 days. After evaporation, the residue was stirred withhot H20 (3 L), cooled down and the product was filtered (51%).

As the rapid development of chemical substances, we look forward to future research findings about 119-39-1

Reference£º
Patent; THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; FOKIN, Valery; SHARPLESS, Barray, K.; ECKMANN, Lars; MIYAMOTO, Yukiko; WO2014/205414; (2014); A1;,
Phthalazine – Wikipedia
Phthalazine | C8H6N2 – PubChem