Phthalazin-1(2H)-one, cas is 119-39-1, it is a common heterocyclic compound, the phthalazine compound, its synthesis route is as follows.,119-39-1
Weighing 2H-phthalazin-1-one (150 mmol), tert-butyl 5-({[(2-chlorophenyl)methoxy]carbonyl}amino)-3,4-dihydroisoquinoline-2(1H)-carboxylate (195 mmol) in reaction bottle, adding DMF100ml, 55 C lower reaction overnight, stopping the reaction, by adding water 100 ml, dichloromethane 200 ml, extraction, separation of the organic phase, the aqueous phase to continue to dichloromethane is used for extraction (3 * 50 ml), the combined organic phase, anhydrous sodium sulfate drying, column chromatography purification obtained title compound.
With the rapid development of chemical substances, we look forward to future research findings about Phthalazin-1(2H)-one
Reference£º
Patent; Nanjing Advanced Biological Materials And Process Equipment Institute Co., Ltd.; Guo Chengjie; (11 pag.)CN109481444; (2019); A;,
Phthalazine – Wikipedia
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