Introduction of a new synthetic route about 5-Nitrophthalazine

89898-86-2, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,89898-86-2 ,5-Nitrophthalazine, other downstream synthetic routes, hurry up and to see

Name is 5-Nitrophthalazine, as a common heterocyclic compound, it belongs to phthalazine compound, and cas is 89898-86-2, its synthesis route is as follows.

B. A solution of 5-nitro-phthalazine (0.175 g, 1 mmol) and SnCl2 (0.57 g, 3 mmol) in concentrated HCl (10 mL) is stirred at room temperature for 2 h. Ice is added to the solution. A solution of 25% NaOH is added to pH 14 (litmus). The solution is cooled for 18 h. The solution is filtered. Aqueous filtrate is extracted twice with EtOAc. EtOAc layers are combined, washed with water, brine, dried over Na2SO4, filtered and concentrated to give phthalazin-5-ylamine (0.050 g).

89898-86-2, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,89898-86-2 ,5-Nitrophthalazine, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; Calvo, Raul R.; Cheung, Wing S.; Player, Mark R.; US2006/116368; (2006); A1;,
Phthalazine – Wikipedia
Phthalazine | C8H6N2 – PubChem