72702-95-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid, cas is 72702-95-5,the phthalazine compound, it is a common compound, a new synthetic route is introduced below.
EXAMPLE 54 Acetyl chloride (10 ml.) was added to stirred methanol (150 ml.) to give a solution of hydrogen chloride in methanol and methyl acetate. 2-(2-Fluoro-4-bromobenzyl)-1,2-dihydro-1-oxophthalazin-4-ylacetic acid (2.1 g.) was added to this solution and the mixture was heated under reflux for 18 hours, and then cooled to room temperature. The solid which crystallized out was separated by filtration and recrystallized from methanol to give methyl 2-(2-fluoro-4-bromobenzyl)-1,2-dihydro-1-oxophthalazin-4-ylacetate (1.4 g.), m.p. 151-153 C.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid, 72702-95-5
Reference£º
Patent; Imperial Chemical Industries Limited; US4251528; (1981); A;,
Phthalazine – Wikipedia
Phthalazine | C8H6N2 – PubChem