The important role of 763114-26-7

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763114-26-7, Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬Which mentioned a new discovery about 763114-26-7

Phthalazinone derivatives pro or its pharmaceutically acceptable salt and its pharmaceutical composition and application (by machine translation)

The invention belongs to the technical field of pharmaceutical chemistry, in particular to a phthalazinone derivative pro or its pharmaceutically acceptable salt, also relates to a pharmaceutical composition and in the preparation of an anti-tumor drug. The present invention provides compounds having the structural formula (I) Of the phthalazinone derivatives prodrugs of good solubility in vivo, after administration into the body, by the metabolic release phthalazine ketone drug molecules, thereby greatly improving the phthalazine ketone group in vivo bioavailability of drug molecules, the phthalazine ketone drug molecules with the in vivo enzyme PARP to not reversible way binding to exert the drug efficacy, anti-tumor activity is prominent. (by machine translation)

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N739 – PubChem