In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 763111-47-3, name is 4-(4-Fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one, introducing its new discovery. COA of Formula: C20H19FN4O2
Phthalazinone derivatives pro or its pharmaceutically acceptable salt and its pharmaceutical composition and application (by machine translation)
The invention belongs to the technical field of pharmaceutical chemistry, in particular to a phthalazinone derivative pro or its pharmaceutically acceptable salt, also relates to a pharmaceutical composition and in the preparation of an anti-tumor drug. The present invention provides compounds having the structural formula (I) Of the phthalazinone derivatives prodrugs of good solubility in vivo, after administration into the body, by the metabolic release phthalazine ketone drug molecules, thereby greatly improving the phthalazine ketone group in vivo bioavailability of drug molecules, the phthalazine ketone drug molecules with the in vivo enzyme PARP to not reversible way binding to exert the drug efficacy, anti-tumor activity is prominent. (by machine translation)
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 763111-47-3, and how the biochemistry of the body works.COA of Formula: C20H19FN4O2
Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N804 – PubChem