A new application about Phthalazine

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Chemistry is traditionally divided into organic and inorganic chemistry. HPLC of Formula: C8H6N2, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 253-52-1

Minisci C-H alkylation of N-heteroarenes with aliphatic alcohols: Via beta-scission of alkoxy radical intermediates

A Minisci-type C-H alkylation reaction of N-heteroarenes with aliphatic alcohols via beta-scission of alkoxy radical intermediates under photoredox-catalyzed conditions was developed. The use of the benziodoxole acetate (BI-OAc) oxidant is critical to achieving high efficiency under mild conditions using a slight excess of an alcohol reactant. Primary, secondary, and tertiary alcohols all are compatible. Reactions of various complex N-heteroarenes including drug molecules and steroid natural products have been demonstrated.

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N192 – PubChem