In heterogeneous catalysis, the catalyst is in a different phase from the reactants. COA of Formula: C17H12BrFN2O3, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 72702-95-5, name is 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid. In an article£¬Which mentioned a new discovery about 72702-95-5
Spiro[fluoreneisothiazolidin]one dioxides: New aldose reductase and L- hexonate dehydrogenase inhibitors
The first examples of spiro[fluorene-9,4′- and -9,5′-isothiazolidin]one dioxides (1 and 2) were synthesized and screened for activity as aldose reductase and L-hexonate dehydrogenase inhibitors. Compared to compounds 1, and 9,5′-compounds 2, synthesized from fluorene-9-sulfonamides by alkylation at C(9) with ethyl bromoacetate followed by cyclization, were more active, but relatively nonselective, inhibitors of aldose reductase and L-hexonate dehydrogenase, with IC50 values for in vitro inhibition of both enzymes on the order of 10-7-10-8 M. However, the isomeric 9,4′-compounds 1, prepared by alkylation of fluorene-9-carboxylic acid esters with bromo- or iodomethanesulfonamide followed by cyclization, were more selective inhibitors of L-hexonate dehydrogenase with IC50 values of about 10-6 M.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 72702-95-5, help many people in the next few years.COA of Formula: C17H12BrFN2O3
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Phthalazine – Wikipedia,
Phthalazine | C8H6N858 – PubChem