Reference of 763111-47-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 763111-47-3, Name is 4-(4-Fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one, molecular formula is C20H19FN4O2. In a Patent£¬once mentioned of 763111-47-3
A phthalazinone hydroxamic acid derivatives and its preparation method and application (by machine translation)
The invention discloses a has a plurality of poly adenosine diphosphate ribose polymerase (PARP) and/or histone deacetylase (HDAC) inhibitory activity of taitai qin alkone different hydroxy wo acid compounds and preparation method and application thereof. The taitai qin alkone different hydroxy wo acid compounds of the formula I as shown in the structural formula, wherein R1 Is a hydrogen atom or a halogen; R2 Is a hydrogen atom or a halogen; Y is an oxygen atom, methylene or fluorine substituted methylene; Z is or G bond is a chemical bond, methylene, fluoro methylene or double bond. In vitro cell proliferation experiment shows that, as shown in formula I compound well inhibit a variety of tumor cell proliferation. Poly adenosine diphosphate ribose polymerase (PARP) and histone deacetylase (HDAC) inhibition experiment I indicates the type compound is shown to poly adenosine diphosphate ribose polymerase (PARP) and/or histone deacetylase (HDAC) have good inhibitory activity of the compound. (by machine translation)
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 763111-47-3. In my other articles, you can also check out more blogs about 763111-47-3
Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N805 – PubChem