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Compound based on ligand-CRBN induced degradation PARP-1 of ligand, as well as preparation method and application thereof (by machine translation)
The compound and the pharmaceutical composition of the CRBN compound disclosed PARP – 1 by the invention can be used for preventing, or treating a human PARP – 1 body, and E3 the compound and the cereblon pharmaceutical composition disclosed by the invention can. be used for preventing or treating a human body and having a great application prospect in, and the field of medicines / PARP – 1, PARP – 1, PARP – 1. (by machine translation)
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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N778 – PubChem