One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Application In Synthesis of 4-Oxo-3,4-dihydrophthalazine-1-carboxylic acid, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 3260-44-4, Name is 4-Oxo-3,4-dihydrophthalazine-1-carboxylic acid, molecular formula is C9H6N2O3
Potent Antifungal Synergy of Phthalazinone and Isoquinolones with Azoles Against Candida albicans
Four phthalazinones (CIDs 22334057, 22333974, 22334032, 22334012) and one isoquinolone (CID 5224943) were previously shown to be potent enhancers of antifungal activity of fluconazole against Candida albicans. Several even more potent analogues of these compounds were identified, some with EC50 as low as 1 nM, against C. albicans. The compounds exhibited pharmacological synergy (FIC < 0.5) with fluconazole. The compounds were also shown to enhance the antifungal activity of isavuconazole, a recently FDA approved azole antifungal. Isoquinolone 15 and phthalazinone 24 were shown to be active against several resistant clinical isolates of C. albicans. Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Application In Synthesis of 4-Oxo-3,4-dihydrophthalazine-1-carboxylic acid, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 3260-44-4, in my other articles.
Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N674 – PubChem