A new application about Phthalazine

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Safety of Phthalazine, you can also check out more blogs about253-52-1

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Safety of Phthalazine. Introducing a new discovery about 253-52-1, Name is Phthalazine

An Amine Group Transfer Reaction Driven by Aromaticity

A stereoselective domino inverse electron-demand Diels-Alder/amine group transfer reaction catalyzed by a bidentate Lewis acid provides 1-amino-1,2-dihydronaphthalenes, a core structure in many bioactive compounds. A concerted mechanism is proposed based on experimental studies as well as DFT computations demonstrating a new general reactivity scheme. The broad scope of the reaction was evaluated by variation of all three starting compounds, phthalazines, aldehydes, and amines. Scalability was demonstrated by a gram scale reaction without diminished yield.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Safety of Phthalazine, you can also check out more blogs about253-52-1

Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N23 – PubChem