Application of 7524-50-7, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 7524-50-7, Name is H-Phe-OMe.HCl, SMILES is N[C@@H](CC1=CC=CC=C1)C(OC)=O.[H]Cl, belongs to phthalazines compound. In a article, author is Munin, Javier, introduce new discover of the category.
Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives
A new series of phthalazine derivatives was synthesized by reaction of phthalic anhydride and different substituted phenylacetic acids to yield the benzyliden-3H-isobenzofuran-1-one intermediates 2a-d. Treatment of them with hydrazine afforded 4-benzyl-2H-phthalazin-1-one derivatives 3a-d, which were substituted with the corresponding aminoalkylalcohol to obtain the (4-benzylphthalazin-1-ylamino)alcohol derivatives 4a-h. In general, these phthalazine derivatives relaxed the contractions produced by phenylephrine both in intact or endothelium-denuded aortic rings. In addition, platelet aggregation induced by thrombin was also inhibited by compounds 4c and 4g.
Application of 7524-50-7, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 7524-50-7.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem