#REF!
Azines and Azoloazines, Part 1: Reactions of Triazolo[3,4-a]phthalazine and Its Derivatives with Carbanions
Triazolo[3,4-a]phthalazine as well as their chloro and nitro derivatives were subjected to the reactions with the carbanions typical for the vicarious nucleophilic substitution (VNS) of hydrogen. The reactions were strongly dependent on the substituents present on the triazolo[3,4-a]phthalazine ring and resulted not only in the substitution of hydrogen but also in exchange of chlorine atom and pyridazine ring scission; the latter process dominated for the unsubstituted triazolophthalazine. Two of the products showed promising stimulating activity towards the central nervous system with no significant toxic effects.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem