Synthetic Route of 198561-07-8, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 198561-07-8, Name is Fmoc-Pra-OH, SMILES is C#CC[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(O)=O, belongs to phthalazines compound. In a article, author is Reddy, Y. Dathu, introduce new discover of the category.
FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF 1-(1H-INDOL-2-YL)-1H-PYRAZOLO[1,2-b]PHTHALAZINE-5,10-DIONES
Facile, efficient, four-component domino reaction of dialkylphthalates, hydrazine hydrate, indole-3-carboxaldehydes, and malononitrile/ethyl cyanoacetate leads to the formation of 1-(1H-indol-2-yl)-1H-pyrazolo [1,2-b] phthalazine-5,10-diones in the presence of InCl3 as catalyst in refluxing ethanol for 1 h in good yields. This four-component domino reaction transformation presumably proceeds via sequential addition, dehydration, condensation, and cyclization steps.
Synthetic Route of 198561-07-8, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 198561-07-8.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem