Reference of 402-49-3, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 402-49-3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene, SMILES is FC(C1=CC=C(CBr)C=C1)(F)F, belongs to phthalazines compound. In a article, author is Kidwai, Mazaahir, introduce new discover of the category.
A Rapid and an Efficient Route to the One-pot, Multicomponent Synthesis of 1H-Pyrazolo[1,2-b]phthalazine-5,10-dione Ring Systems
CAN is found to be an efficient catalyst for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives via one-pot coupling reaction of phthalhydrazide, aromatic aldehydes, and malononitrile or ethyl cyanoacetate in PEG as solvent. The major attributes of this synthetic protocol are the use of nontoxic, inexpensive, and readily available catalyst, mild conditions, easy work up, improved yields, and the PEG 400 as solvent that is environmentally benign as well as recyclable.
Reference of 402-49-3, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 402-49-3 is helpful to your research.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem