Synthetic Route of 66-99-9, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 66-99-9, Name is 2-Naphthaldehyde, SMILES is O=CC1=CC=C2C=CC=CC2=C1, belongs to phthalazines compound. In a article, author is Wang, Haitao, introduce new discover of the category.
Enantioselective Fluorocyclizations Mediated by Amino-Acid-Derived Phthalazine
Novel amino-acid-derived phthalazine reagents have been designed and synthesized for the enantioselective fluorocyclizations of prochiral indoles. The scope of reaction is evidenced by 28 examples of fluorinated furoindole and pyrroloindole heterocycles bearing various functionalities with up to 99% ee. The resulting enantioenriched fluorinated products are found to be potent AChE inhibitors. Advantages of the current new chiral reagents include ease in the synthesis of analogues and readily tunable steric/electronic demands.
Synthetic Route of 66-99-9, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 66-99-9.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem