Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, SDS of cas: 4474-86-6, 4474-86-6, Name is N-Cbz-D-Asparagine, SMILES is O=C(N)C[C@H](C(O)=O)NC(OCC1=CC=CC=C1)=O, belongs to phthalazines compound. In a document, author is Soltanzadeh, Zahra, introduce the new discover.
Solvent-free organic salt media mono symmetrical aza-Michael: synthesis of new N-mono substituted phthalhydrazide derivatives
In this paper, C-N bond formation between 2,3-dihydrophthalazine-1(4H),4-dione (phthalhydrazide) and alpha,beta-unsaturated esters was investigated and a new series of phthalazine derivatives was synthesized using an efficient and simple method under solvent-free conditions. An aza-Michael addition of phthalhydrazide to both acrylic and fumaric esters led to N-monosubstituted phthalhydrazides (as mono-Michael adduct) in the presence of tetrabutylammonium bromide as a high polar media, and 1,4-diaza-bicyclo[2,2,2] octane as an available organic base. In this reaction, the N1,N2-bis-Michael adduct was not observed at all. Also, reactions were performed at 90 degrees C and yields of products were good to excellent.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 4474-86-6. SDS of cas: 4474-86-6.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem