Electric Literature of 90-64-2, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 90-64-2, Name is 2-Hydroxy-2-phenylacetic acid, SMILES is C1=CC=CC=C1C(C(O)=O)O, belongs to phthalazines compound. In a article, author is Abbasi, Marzieh, introduce new discover of the category.
Synthesis, characterization and in vitro antibacterial activity of novel phthalazine sulfonamide derivatives
Several phthalazine derivatives were synthesized by the one-pot three-component condensation in good to high yields in the presence of diatomite-SO3H as a solid acid catalyst. Then, a series (n= 14) of phthalazine sulfonamides were synthesized by the reaction phthalazine sulfonyl chloride and various amines under solvent-free conditions. The prepared compounds were screened for antibacterial activity against Escherichia coli (E. coli ATCC 25922) and Staphylococcus aureus (S. aureus ATCC 5213) as gram negative and positive respectively. Also, in silico physicochemical parameters of synthesized compounds were studied to predict absorption and permeability using Molinspiration online property calculation server.
Electric Literature of 90-64-2, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 90-64-2 is helpful to your research.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem