Chemistry, like all the natural sciences, Safety of 4,4′-Methylenebis(2-methylaniline), begins with the direct observation of nature— in this case, of matter.838-88-0, Name is 4,4′-Methylenebis(2-methylaniline), SMILES is NC1=CC=C(CC2=CC=C(C(C)=C2)N)C=C1C, belongs to phthalazine compound. In a document, author is Vafaee, Asieh, introduce the new discover.
An Efficient and High-yielding One-pot Synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones Catalyzed by Sodium Hydrogen Carbonate under Solvent-free Conditions
Sodium hydrogen carbonate, NaHCO3, efficiently catalyzes the one-pot, three-component reaction of phthalhydrazide, an aromatic aldehyde, and malononitrile or ethyl cyanoacetate under solvent-free conditions, to afford the corresponding 1H-pyrazolo[1,2-b]phthalazine-5,10-diones in high yields. Easy work up, inexpensive and readily available catalyst and avoiding the use of harmful organic solvents are other advantages of this simple procedure.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 838-88-0. Safety of 4,4′-Methylenebis(2-methylaniline).
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem