In an article, author is Behalo, Mohamed S., once mentioned the application of 369-34-6, Name is 3,4-Difluoronitrobenzene, molecular formula is C6H3F2NO2, molecular weight is 159.09, MDL number is MFCD00007198, category is phthalazine. Now introduce a scientific discovery about this category, Product Details of 369-34-6.
An efficient one-pot catalyzed synthesis of 2,5-disubstituted-1,3,4-oxadiazoles and evaluation of their antimicrobial activities
One-pot synthesis of 1,3,4-oxadiazole derivatives was achieved by treatment of 2-((4-(phenoxathiin-2-yl) phthalazin-1-yl)oxy) acetohydrazide with aromatic aldehydes in the presence of cerium(IV) ammonium nitrate in dichloromethane. This facile method was confirmed by the cyclization-oxidation reaction of the corresponding hydrazone by cerium(IV) ammonium nitrate to afford the same 1,3,4-oxadiazoles. Also, the reaction of 2-((4-(phenoxathiin-2-yl)phthalazin-1-yl) oxy) acetohydrazide with aromatic carboxylic acids in the presence of cerium(IV) ammonium nitrate in polyethylene glycol afforded 1,3,4-oxadiazole derivatives. The structural formulae of all products were confirmed and characterized by elemental analyses and spectral data. Most of the synthesized products were evaluated for their antibacterial and antifungal activities and showed potent to weak activity.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem