Synthetic Route of 83-53-4, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 83-53-4, Name is 1,4-Dibromonaphthalene, SMILES is C1=CC=CC2=C(C=CC(=C12)Br)Br, belongs to phthalazine compound. In a article, author is He, Zeng-Yang, introduce new discover of the category.
Highly Regioselective Carbamoylation of Electron-Deficient Nitrogen Heteroarenes with Hydrazinecarboxamides
The use of hydrazinecarboxamides as a new class of carbamoylating agents has been established through the dehydrazinative Minisci reaction of electron-deficient nitrogen heteroarenes. A wide range of electron-deficient nitrogen heteroarenes, including isoquinoline, quinoline, pyridine, phenanthridine, quinoxaline, and phthalazine, underwent copper/acid-catalyzed oxidative carbamoylation with hydrazinecarboxamide hydrochlorides to afford structurally diverse nitrogen-heteroaryl carboxamides as single regioisomers in moderate to excellent yields. The functional group tolerance was substantially demonstrated in the direct carbamoylation of quinine obviating multistep sequences involving protecting groups and prefunctionalization of the heterocycle.
Synthetic Route of 83-53-4, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 83-53-4 is helpful to your research.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem