Application of 83-53-4, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 83-53-4, Name is 1,4-Dibromonaphthalene, SMILES is C1=CC=CC2=C(C=CC(=C12)Br)Br, belongs to phthalazine compound. In a article, author is Behalo, Mohamed S., introduce new discover of the category.
An efficient one-pot catalyzed synthesis of 2,5-disubstituted-1,3,4-oxadiazoles and evaluation of their antimicrobial activities
One-pot synthesis of 1,3,4-oxadiazole derivatives was achieved by treatment of 2-((4-(phenoxathiin-2-yl) phthalazin-1-yl)oxy) acetohydrazide with aromatic aldehydes in the presence of cerium(IV) ammonium nitrate in dichloromethane. This facile method was confirmed by the cyclization-oxidation reaction of the corresponding hydrazone by cerium(IV) ammonium nitrate to afford the same 1,3,4-oxadiazoles. Also, the reaction of 2-((4-(phenoxathiin-2-yl)phthalazin-1-yl) oxy) acetohydrazide with aromatic carboxylic acids in the presence of cerium(IV) ammonium nitrate in polyethylene glycol afforded 1,3,4-oxadiazole derivatives. The structural formulae of all products were confirmed and characterized by elemental analyses and spectral data. Most of the synthesized products were evaluated for their antibacterial and antifungal activities and showed potent to weak activity.
Application of 83-53-4, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 83-53-4 is helpful to your research.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem