Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 1821-12-1, Name is 4-Phenylbutanoic acid, molecular formula is C10H12O2, belongs to phthalazine compound, is a common compound. In a patnet, author is Abida, once mentioned the new application about 1821-12-1, COA of Formula: C10H12O2.
Synthesis of some pyridazine derivatives as antioxidants and antimicrobial agents
Purpose: To prepare some pyridazine derivatives as antioxidant and antimicrobial agents. Methods: The coupling of aryl diazonium salts with diethyl 2-cyano-3-methylglutaconate afforded pyridazine-5-carbonitrile derivatives (3a-e). The methyl function in the pyridazine derivatives (3a-e) reacted with cinnamonitriles to yield phthalazine derivatives (6a-h). Imino-pyridazine derivatives (9a-h) were obtained by reacting 2-aminoprop-1-ene-1,1,3-tricarbonitrile along with aryl diazonium salts (1a-h). Structure elucidation was done by spectral analysis. The 1,1-diphenyl-2-picryl hydrazyl (DPPH) technique was employed to assess antioxidant effect, while evaluation of antimicrobial activity was carried out by serial dilution technique. Results: Compounds, 6f (IC50 = 12.68 mu g/mL; p < 0.05), 6a (IC50 = 14.23 mu g/mL; p < 0.05), and 3c (IC50 = 14.34 mu g/mL; p < 0.05) displayed good antioxidant activity compared to ascorbic acid (IC50 = 12.45 mu g/mL; p < 0.05). Based on the zone of inhibition, compound 6c (p < 0.05) displayed higher activity than ofloxacin (p < 0.05) against E. coli. Conclusion: The presence of an oxo group and carboxylate group plays an important role in the antioxidant activity of these compounds. Compounds 6a, 6f, and 3c can potentially serve as lead compounds for the development of promising antioxidants. We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 1821-12-1. The above is the message from the blog manager. COA of Formula: C10H12O2.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem