The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Recommanded Product: 4-Bromophenylacetic acid, 1878-68-8, Name is 4-Bromophenylacetic acid, SMILES is OC(=O)CC1=CC=C(Br)C=C1, in an article , author is Heirati, Seyedeh Zahra Dalil, once mentioned of 1878-68-8.
In this work, a series of 2H-indazolo[2,1-b]phthalazine-triones and Biginelli-like products were efficiently synthesized for the first time using O-Sulfonic acid poly(4-vinylpyrrolidonium) chloride ([PVP-SO3H]Cl) as an eco-friendly polymer-supported catalyst. At first, the catalyst preparation process was optimized based on the chlorosulfonic acid amount and the sulfonation time to obtain a catalyst with the maximum acidity content. The maximum acidity content for [PVP-SO3H]Cl was obtained to be 3.31 mmol g(-1). Then, the optimized [PVP-SO3H]Cl was used as a catalyst for the synthesis of a series of 2H-indazolo[2,1-b]phthalazine-triones and Biginelli-like products. It was observed that only 10 mg of the catalyst was enough to catalyze these reactions under mild conditions, and the corresponding products were obtained in high to excellent yields. Moreover, the catalyst could be repeatedly used for at least five times without a noticeable decrease in its catalytic activity.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 1878-68-8, you can contact me at any time and look forward to more communication. Recommanded Product: 4-Bromophenylacetic acid.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem