Never Underestimate The Influence Of 2-Benzamidoacetic acid

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 495-69-2, Name is 2-Benzamidoacetic acid, molecular formula is C9H9NO3. In an article, author is Dam, Binoyargha,once mentioned of 495-69-2, Category: phthalazines.

Nano-organocatalyzed one-pot four-component reactions for the synthesis of phthalazine-trione/dione derivatives have been devised for the first time from easily accessible starting materials under solvent-free conditions. This methodology showed very good substrate scope and high degree of tolerance for a variety of aldehydes (including aliphatic and heteroaromatic aldehydes) and active methylene compounds. Moreover, the catalyst can be easily separated from the reaction mixture because of its highly paramagnetic nature, by using an external magnet, and can be reused in five more consecutive runs without much decrease in catalytic activities. Other significant advantages of this method are shorter reaction time, good yield, simple work-up procedure, easy catalyst handling etc.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem