The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic, and theoretical assessments of solvent structures and their interactions with reaction intermediates and transition states. 36809-26-4, Name is (4-Bromophenyl)diphenylamine, molecular formula is C18H14BrN, belongs to phthalazine compound. In a document, author is Behalo, Mohamed S., introduce the new discover, Category: phthalazines.
A new series of phthalazine derivatives was synthesized from the reaction of 1-chloro-4-(4-phenoxyphenyl)phthalazine as a reactive starting material with different carbon, nitrogen, oxygen, and sulfur nucleophiles. The structural formulae of all products were confirmed and characterized by elemental analyses and spectral data (IR, H-1 NMR, C-13 NMR, and mass spectra). Some of the synthesized derivatives were screened for their antitumor activity against four human tumor cell lines using MTT assay. In comparison with doxorubicin as standard drug, compounds 1, 20, and 25 showed the most potent cytotoxic effect. In addition, investigation of antioxidant activity revealed that hydrazinylphthalazine 20 has the highest activity.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 36809-26-4. The above is the message from the blog manager. Category: phthalazines.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem