The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic, and theoretical assessments of solvent structures and their interactions with reaction intermediates and transition states. 62-23-7, Name is 4-Nitrobenzoic acid, molecular formula is C7H5NO4, belongs to phthalazine compound. In a document, author is Banerjee, Dipanwita, introduce the new discover, COA of Formula: https://www.ambeed.com/products/62-23-7.html.
The present report articulates a potential and green method for the synthesis of pyrazolo[1,2-b]phthalazine-5,10-dione by one-pot four component reaction involving phthalimide (1), hydrazine hydrate (2), aldehyde (3) and malononitrile (4). Proline has been utilized as organo-catalyst in a mixed solvent of ethanol and water in the ratio of 2:1 at 80 degrees C. The reaction reveals excellent reactivity, functional group tolerance, and quite high yields without using any extreme reaction condition like strong acid or metal catalyst. Eighteen compounds have been synthesised by this method including five new compounds.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 62-23-7. COA of Formula: https://www.ambeed.com/products/62-23-7.html.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem