Healthcare careers for chemists are once again largely based in laboratories, SDS of cas: 117-34-0, although increasingly there is opportunity to work at the point of care, helping with patient investigation. 117-34-0, Name is 2,2-Diphenylacetic acid, SMILES is O=C(O)C(C1=CC=CC=C1)C2=CC=CC=C2, belongs to phthalazine compound. In a document, author is Mogilaiah, K., introduce the new discover.
A simple and highly efficient procedure has been described for the synthesis of 3-(3-aryl[1,8]naphthyridin-2-yl)-7-[1-[1,4-dioxo-1, 2, 3, 4-tetrahydro-6-phthalazinyl]-2, 2, 2-trifluoro-1-(trifluoromethyl)ethyl]-2-(3-aryl[1,8]naphthyridin-2-yl)-1,2,3,4-tetrahydro-1,4-phthalazinediones 3 by the condensation of 3-aryl-2-hydrazino-1,8-naphthyridines 1 with 4,4 ‘-(hexafluoroisopropylidene)diphthalic anhydride 2 in 2:1 molar ratio in the presence of catalytic amount of DMF under microwave irradiation/ in presence of catalytic amount of PTSA in the solid state at RT under grinding conditions. The products have been obtained in very good yields and in a state of high purity. The structures of the compounds 3 have been established on the basis of their spectral (IR and H-1 NMR) and analytical data. The compounds 3 have been screened for their antibacterial activity.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem