Month: September 2021

In 2019.0 CHEM-EUR J published article about CARBON-DIOXIDE; IONIC LIQUIDS; REDUCTIVE FUNCTIONALIZATION; FLUORIDE; KETONES; HYDROSILANES; HYDROSILYLATION; METHYLATION; FORMAMIDES; ACTIVATION in [Hulla, Martin; Ortiz, Daniel; Vasilyev, Dmitry; Dyson, Paul J.] Ecole Polytech Fed Lausanne, Inst Chem & Chem Engn, CH-1015 Lausanne, Switzerland; [Katsyuba, Sergey] RAS, FRC, Kazan Sci Ctr, Arbuzov Inst Organ & Phys Chem, Arbuzov St 8, Kazan 420088, Russia in 2019.0, Cited 57.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. HPLC of Formula: C7H5NO4

N-formylation of amines with CO2 is base-catalyzed and studies of salt catalysts reveal that the reaction is efficiently catalyzed by free floating anions of high basicity, as represented in the cover image. More information can be found in the Full Paper by P. J. Dyson et al. (DOI: 10.1002/chem.201901686).

About 4-Nitrobenzoic acid, If you have any questions, you can contact Hulla, M; Ortiz, D; Katsyuba, S; Vasilyev, D; Dyson, PJ or concate me.. HPLC of Formula: C7H5NO4

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

An article Asymmetric Michael Addition of Unactivated Ketones with beta-Nitrostyrenes Mediated by Bifunctional L-Prolinamide Organocatalysts WOS:000516865300011 published article about ENANTIOSELECTIVE CONJUGATE ADDITION; CARBONYL-COMPOUNDS; NITROOLEFINS; CATALYSIS; CYCLOHEXANONE; NITROALKANES; CONSTRUCTION; DERIVATIVES; ACID; 3-HYDROXY-2-OXINDOLES in [Rani, Dixita; Bhargava, Meha; Agarwal, Jyoti] Panjab Univ, Dept Chem, Chandigarh 160014, India; [Rani, Dixita; Bhargava, Meha; Agarwal, Jyoti] Panjab Univ, Ctr Adv Studies, Chandigarh 160014, India in 2020.0, Cited 102.0. SDS of cas: 62-23-7. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7

The catalytic activity of two types of L-prolinamide organocatalysts was investigated for asymmetric Michael addition reaction of cyclic/acyclic ketones with beta-nitrostyrens. L-Prolinamides bearing amino groups on phenyl ring worked well, though their catalytic efficiency as well as selectivity was found to be dependent upon the position of amine group to the amide bond. Organocatalyst having -NH2 group ortho to amide bond provided the best results. Substrate scope was also studied by performing the reaction of various beta-nitrostyrenes with ketones to afford the corresponding Michael adducts in excellent yields with very high diastereoselectivities and enantioselectivities in almost all cases.

SDS of cas: 62-23-7. About 4-Nitrobenzoic acid, If you have any questions, you can contact Rani, D; Bhargava, M; Agarwal, J or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

An article Synthetic aluminosilicate based geopolymers – Second generation geopolymer HPLC stationary phases WOS:000482179800023 published article about INTERACTION LIQUID-CHROMATOGRAPHY; POROUS GRAPHITIC CARBON; RETENTION BEHAVIOR; PERFORMANCE; METAKAOLIN; COLUMNS; SELECTIVITY; SUSPENSION; PACKING; MODE in [Thakur, Nimisha; Wahab, M. Farooq; Khanal, Durga D.; Armstrong, Daniel W.] Univ Arlington, Dept Chem & Biochem, Arlington, TX 76019 USA in 2019.0, Cited 46.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. Computed Properties of C7H5NO4

A survey of existing stationary phases classified by the United States Pharmacopeia reveals that 120 groups of chromatographic supports mostly utilize silica-silane chemistry, polymeric materials along with some niche metal oxides. In this work, the synthesis and characterization of transition-metal free geopolymers as a new class of stationary phases for hydrophilic interaction liquid chromatography and normal phase separations is reported. The geopolymers were synthesized by reaction of synthetic aluminosilicate with potassium silicate (fumed silica dissolved in KOH) in a water-in-oil emulsion. For comparative purposes of peak shapes, a geopolymer from natural metakaolin was also synthesized. The geopolymers were examined by X-ray diffraction, energy dispersive spectroscopy, laser diffraction, and N-2-adsorption isotherms. This two-step approach gives spherical microparticles with surface area and pore size comparable to silica phases (150 m(2)/g and 120 angstrom respectively). Both synthetic aluminosilicates based and natural metakaolin based geopolymers occupy a unique spot in the HILIC selectivity chart when compared to 35 HILIC phases. An additional promising feature of geopolymers is high pH and temperature stability which are used to tune selectivity for small polar analytes. High pH separations are shown with carboxylic acids. Geopolymers also show mixed mode behavior in retention with ion-exchange properties in purely aqueous mobile phases. The separation of derivatized sugars is demonstrated and compared with porous graphitic carbon (Hypercarb (TM)) as another pH-stable stationary phase. (C) 2019 Elsevier B.V. All rights reserved.

Computed Properties of C7H5NO4. About 4-Nitrobenzoic acid, If you have any questions, you can contact Thakur, N; Wahab, MF; Khanal, DD; Armstrong, DW or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Formula: C7H5NO4. Kumar, M; Verma, S; Verma, AK in [Kumar, Manoj; Verma, Shalini; Verma, Akhilesh K.] Univ Delhi, Dept Chem, Delhi 110007, India published Ru(II)-Catalyzed Oxidative Olefination of Benzamides: Switchable Aza-Michael and Aza-Wacker Reaction for Synthesis of Isoindolinones in 2020.0, Cited 65.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7.

Selective tandem oxidative C-H olefination-azaMichael/aza-Wacker reaction of N-arylbenzamides is achieved by fine-tuning between base and additive to access valuable 3-oxoisoindolinyls and 3-oxoisoindolinylidenes, respectively. Careful optimization and control experiments provides a guiding principle in the design of a proposed catalytic cycle. The copper-iminium complex acting as a precursor for the binding of Ru catalyst was isolated and confirmed by X-ray diffraction. The versatility of this catalytic system has been demonstrated by the synthesis of biologically relevant molecules.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Kumar, M; Verma, S; Verma, AK or concate me.. Formula: C7H5NO4

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Authors Matsuno, R; Kokubo, Y; Kumagai, S; Takamatsu, S; Hashimoto, K; Takahara, A in AMER CHEMICAL SOC published article about HOFMEISTER SERIES; LIQUIDS; WATER; DISSOLUTION; PROTEINS; SOLVENTS; POLYOLS; MODEL in [Matsuno, Ryosuke; Takahara, Atsushi] Kyushu Univ, Inst Mat Chem & Engn, Fukuoka 8190395, Japan; [Matsuno, Ryosuke; Hashimoto, Kazunobu] Kyushu Univ, KOINE Project Div, Global Innovat Ctr, Kasuga, Fukuoka 8168580, Japan; [Kokubo, Yota; Kumagai, Shinji; Takamatsu, Shigeaki] Sumitomo Riko Co, Komaki, Aichi 4858550, Japan in 2020.0, Cited 41.0. Name: 4-Nitrobenzoic acid. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7

Ionic liquid monomers with ion pair interaction energies ranging from 73.0 to 101.4 kcal/mol were designed by using the calculated electrostatic potential (ESP) values of the component ions. The ionic liquid monomers were classified as cationic monomers with an anionic counterion and anionic monomers with a cationic counterion. We evaluated the calculated ion pair interaction energy using counterion mobility as an indicator. One component of the ion pair was fixed onto a dielectric elastomer by using alkoxysilane coupling agents, while the counterion remained free to move under the applied voltage. We then measured the relative dielectric constant at 0.01 Hz, which is an indicator of the mobility of the counterion. The results showed a good correlation between the calculated ion pair interaction energy and the relative dielectric constant. The lower the ion pair interaction energy is, the easier the dissociation of the ion pair. From this result, we were able to prove the correlation between the calculated ion pair interaction energy and the mobility of the counterion. Furthermore, classification of other ion pair compounds and polyelectrolyte polymer brushes that follow the anion Hofmeister series based on ion pair interaction energies revealed the correlation between physical properties and the ionic structure. Various ionic compounds with desired physical properties can be designed by using the calculated ion pair interaction energies.

Name: 4-Nitrobenzoic acid. About 4-Nitrobenzoic acid, If you have any questions, you can contact Matsuno, R; Kokubo, Y; Kumagai, S; Takamatsu, S; Hashimoto, K; Takahara, A or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Formula: C7H5NO4. Recently I am researching about C-H BONDS; BENZOIC-ACID; MOLECULAR-OXYGEN; N-HYDROXYPHTHALIMIDE; SELECTIVE OXIDATION; METAL-FREE; PHOTOOXIDATION; DERIVATIVES; COBALT; OXIDE, Saw an article supported by the National Key Research and Development Program of China [2017YFC0210900]. Published in GEORG THIEME VERLAG KG in STUTTGART ,Authors: Zheng, K; Yan, XY; Zhang, GF; Yan, XH; Li, XQ; Xu, XS. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid

A mild and metal-free procedure is reported for the aerobic oxidation of substituted toluenes to carboxylic acids by using CBr (4) as initiator under irradiation from a 400 nm blue light-emitting diode.

Formula: C7H5NO4. About 4-Nitrobenzoic acid, If you have any questions, you can contact Zheng, K; Yan, XY; Zhang, GF; Yan, XH; Li, XQ; Xu, XS or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

An article Total syntheses of several iridolactones and the putative structure of noriridoid scholarein A: an intramolecular Pauson-Khand reaction based one-stop synthetic solution WOS:000476549400014 published article about NATURALLY-OCCURRING IRIDOIDS; ENANTIOSELECTIVE TOTAL-SYNTHESIS; SOLVOMERCURATION-DEMERCURATION; ISOIRIDOMYRMECIN; STEREOCHEMISTRY; IRIDOMYRMECIN; SECOIRIDOIDS; OXIDATION; ACID in [Salam, Abdus; Ray, Sayan; Abu Zaid, Md; Kumar, Dileep; Khan, Tabrez] Indian Inst Technol Bhubaneswar, Sch Basic Sci, Organ Synth Lab, Khurdha 752050, Odisha, India in 2019.0, Cited 55.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. Safety of 4-Nitrobenzoic acid

A simple and general approach towards the total syntheses of several iridolactones such as (+/-)-boschnialactone, (+/-)-7-epi-boschnialactone, (+/-)-teucriumlactone, (+/-)-iridomyrmecin, (+/-)-isoboonein, (+/-)-7-epi-argyol, (+/-)-scabrol A, (+/-)-7-epi-scabrol A, and (+/-)-patriscabrol as well as the putative structure of scholarein A is delineated. The synthetic strategy features a diastereoselective intramolecular Pauson-Khand reaction (IPKR) to construct the iridoid framework followed by some strategic synthetic manipulations to access the targeted monoterpenes including those having diverse oxy-functionalization patterns and with 3-5 contiguous stereogenic centres in a highly stereocontrolled manner. Also, the present endeavour includes the first total synthesis of scabrol A.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Salam, A; Ray, S; Abu Zaid, M; Kumar, D; Khan, T or concate me.. Safety of 4-Nitrobenzoic acid

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

In 2019 Z PHYS CHEM published article about CHARGE-TRANSPORT PROPERTIES; PLATELET-AGGREGATION; MOLECULAR DOCKING; CROSS-TALK; ANTIOXIDANTS; RESONANCE; ASPIRIN; DRUGS in [Ramzan, Ayesha; Nazeer, Areesha; Munawar, Munawar A.; Khan, Misbahul A.; Basra, Muhammad Asim Raza] Univ Punjab, Inst Chem, Quaid E Azam New Campus, Lahore 54590, Pakistan; [Khan, Misbahul A.] Islamia Univ Bahawalpur, Dept Chem, Bahawalpur 63100, Pakistan; [Irfan, Ahmad] King Khalid Univ, Fac Sci, Dept Chem, POB 9004, Abha 61413, Saudi Arabia; [Al-Sehemi, Abdullah G.] King Khalid Univ, RCAMS, POB 9004, Abha 61413, Saudi Arabia; [Verpoort, Francis; Khatak, Zafar A.] Wuhan Univ Technol, State Key Lab Adv Technol Mat Synth & Proc, Lab Organometall Catalysis & Ordered Mat, Wuhan 430070, Hubei, Peoples R China; [Ahmad, Aftab] Univ Punjab, Ctr Excellence Mol Biol, Lahore, Pakistan in 2019, Cited 51. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. Recommanded Product: 4-Nitrobenzoic acid

A novel series of 2-(3-methyl-1,6-diphenyl-1H-pyrazolo[3,4-b]pyridin4-yl)-5-aryl-1,3,4-oxadiazoles (4a-4h) has been synthesized from corresponding hydrazones (3a-3h) and evaluated their antiplatelet aggregation effect induced by arachidonic acid and collagen. Spectral data and elemental evaluation were used to confirm the structure of the compounds while molecular docking against cyclooxygenase 1 and 2 (COX1 & COX2) and quantitative structure-activity relationship (QSAR) were performed in describing their antiplatelet potential. All synthesized compound exhibited more than 50% platelet aggregation inhibition against both arachidonic acid and collagen. Antiplatelet activities results showed that 4b and 4f compounds have highest % inhibition against arachidonic acid. High Egap and ionization potential values showed that the compound 4d, 4e and 4f were supposed to be more active and good electron donor while 4b, 4c, 4d, 4e, 4g and 4h might be more active due to more electrophilic sites. Interaction with more than one residues in the binding pocket of COX-1 in comparison with aspirin and ligand efficacy (LE) consequences showed that compounds have excellent action potential for COX-1. Computational evaluations are in good agreement with antiplatelet activities of the compounds. All compounds might be promising antiplatelet agents especially 4b, 4f and helpful in the synthesis of new drugs for the treatment of cardiovascular diseases (CVDs).

Recommanded Product: 4-Nitrobenzoic acid. About 4-Nitrobenzoic acid, If you have any questions, you can contact Ramzan, A; Nazeer, A; Irfan, A; Al-Sehemi, AG; Verpoort, F; Khatak, ZA; Ahmad, A; Munawar, MA; Khan, MA; Basra, MAR or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

COA of Formula: C7H5NO4. Recently I am researching about ENANTIOSELECTIVE ACYL TRANSFER; ASYMMETRIC ESTERIFICATION; PIVALIC ANHYDRIDE; FACILE SYNTHESIS; DIPHENYLACETIC ACID; CARBOXYLIC-ACIDS; BASICITY SCALE; ALCOHOLS; SECONDARY; DERIVATIVES, Saw an article supported by the ERC under European Union/E.R.C. [279850]; Chinese Scholarship Scheme; University of St Andrews; Royal SocietyRoyal Society of LondonEuropean Commission. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Qu, S; Greenhalgh, MD; Smith, AD. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid

An operationally simple isothiourea-catalysed acylative kinetic resolution of unprotected 1,1 ‘-biaryl-2,2 ‘-diol derivatives has been developed to allow access to axially chiral compounds in highly enantioenriched form (s values up to 190). Investigation of the reaction scope and limitations provided three key observations: i) the diol motif of the substrate was essential for good conversion and high s values; ii) the use of an alpha,alpha-disubstituted mixed anhydride (2,2-diphenylacetic pivalic anhydride) was critical to minimize diacylation and give high selectivity; iii) the presence of substituents in the 3,3 ‘-positions of the diol hindered effective acylation. This final observation was exploited for the highly regioselective acylative kinetic resolution of unsymmetrical biaryl diol substrates bearing a single 3-substituent. Based on the key observations identified, acylation transition state models have been proposed to explain the atropselectivity of this kinetic resolution.

COA of Formula: C7H5NO4. About 4-Nitrobenzoic acid, If you have any questions, you can contact Qu, S; Greenhalgh, MD; Smith, AD or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Recently I am researching about MULTIDRUG-RESISTANCE; NATURAL-PRODUCTS; MACROCYCLIC DITERPENES; BIOLOGICAL-ACTIVITY; MODULATION; PLANTS, Saw an article supported by the National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China (NSFC) [81773594, U1703111, U1803122, 81773637]; Program for Liaoning Innovation Talents in University [LR2016002]; Liaoning Province Natural Science FoundationNatural Science Foundation of Liaoning Province [2019-MS-299]; Liaoning Revitalization Talents Program [XLYC1807182]; Shenyang Planning Project of Science and Technology [18-013-0-46]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Wang, W; Wu, YL; Li, C; Yang, YY; Li, XZ; Li, H; Chen, LX. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid. Application In Synthesis of 4-Nitrobenzoic acid

Euphorbia factor L-3, a lathyrane diterpenoid extracted from Euphorbia lathyris, was found to display good anti-inflammatory activity with very low cytotoxicity. To find more potent anti-inflammatory drugs, two series of Euphorbia factor L-3 derivatives with fatty and aromatic acids were designed and synthesized. Among them, lathyrane derivative 5n exhibited most potent inhibition on LPS-induced NO production in RAW264.7 cells with no obvious cytotoxicity. To determine the key characteristics of Euphorbia factor L-3 derivatives that contribute to anti-inflammatory activity, we conducted a structure-activity relationship study of these compounds.

Application In Synthesis of 4-Nitrobenzoic acid. About 4-Nitrobenzoic acid, If you have any questions, you can contact Wang, W; Wu, YL; Li, C; Yang, YY; Li, XZ; Li, H; Chen, LX or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem