An article Mannich base Cu(II) complexes as biomimetic oxidative catalyst WOS:000469408500017 published article about CATECHOL OXIDASE ACTIVITY; GALACTOSE-OXIDASE; SCHIFF-BASE; DICOPPER(II) COMPLEXES; COPPER(II) COMPLEXES; CRYSTAL-STRUCTURE; POLYPHENOL OXIDASE; METAL-COMPLEXES; MONONUCLEAR; DINUCLEAR in [Kundu, Bidyut Kumar; Ranjan, Rishi; Mobin, Shaikh M.; Mukhopadhyay, Suman] Indian Inst Technol Indore, Sch Basic Sci, Discipline Chem, Khandwa Rd, Indore 453552, Madhya Pradesh, India; [Mukherjee, Attreyee] Ananda Mohan Coll, Dept Chem, Kolkata 700009, India; [Mukhopadhyay, Suman] Indian Inst Technol Indore, Sch Engn, Discipline Biosci & Biomed Engn, Khandwa Rd, Indore 453552, Madhya Pradesh, India in 2019.0, Cited 58.0. Formula: C7H5NO4. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7
Galactose Oxidase (GOase) and catechol oxidase (COase) are the metalloenzymes of copper having monomeric and dimeric sites of coordination, respectively. This paper summarizes the results of our studies on the structural, spectral and catalytic properties of new mononuclear copper (II) complexes [CuL(OAc)] (1), and [CuL2] (2), (HL = 2,4-dichloro-6-{[(2′-dimethyl-aminoethyl)methylamino]methyl}-phenol) which can mimic the functionalities of the metalloenzymes GOase and COase. The structure of the compounds has been elucidated by X-ray crystallography and the mimicked Cu(II) catalysts were further characterized by EPR. These mimicked models were used for GOase and COase catalysis. The GOase catalytic results were identified by GC MS and, analyzed by HPLC at room temperature. The conversion of benzyl alcohol to benzaldehyde were significant in presence of a strong base, Bu4NOMe in comparison to the neutral medium. Apart from that, despite of being monomeric in nature, both the homogeneous catalysts are very prone to participate in COase mimicking oxidation reaction. Nevertheless, during COase catalysis, complex 1 was found to convert 3,5-ditertarybutyl catechol (3,5-DTBC) to 3,5-ditertarybutyl quinone (3,5-DTBQ) having greater rate constant, k(cat) or turn over number (TON) value over complex 2. The generation of reactive intermediates during COase catalysis were accounted by electrospray ionization mass spectrometry (ESI-MS). Through mechanistic approach, we found that H2O2 is the byproduct for both the GOase and COase catalysis, thus, confirming the generation of reactive oxygen species during catalysis. Notably, complex 1 having mono-ligand coordinating atmosphere has superior catalytic activity for both cases in comparison to complex 2, that is having di-ligand environment.
About 4-Nitrobenzoic acid, If you have any questions, you can contact Kundu, BK; Ranjan, R; Mukherjee, A; Mobin, SM; Mukhopadhyay, S or concate me.. Formula: C7H5NO4
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem