Application In Synthesis of 4-Nitrobenzoic acid. I found the field of Chemistry very interesting. Saw the article Asymmetric Michael Addition of Unactivated Ketones with beta-Nitrostyrenes Mediated by Bifunctional L-Prolinamide Organocatalysts published in 2020.0, Reprint Addresses Agarwal, J (corresponding author), Panjab Univ, Dept Chem, Chandigarh 160014, India.; Agarwal, J (corresponding author), Panjab Univ, Ctr Adv Studies, Chandigarh 160014, India.. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid.
The catalytic activity of two types of L-prolinamide organocatalysts was investigated for asymmetric Michael addition reaction of cyclic/acyclic ketones with beta-nitrostyrens. L-Prolinamides bearing amino groups on phenyl ring worked well, though their catalytic efficiency as well as selectivity was found to be dependent upon the position of amine group to the amide bond. Organocatalyst having -NH2 group ortho to amide bond provided the best results. Substrate scope was also studied by performing the reaction of various beta-nitrostyrenes with ketones to afford the corresponding Michael adducts in excellent yields with very high diastereoselectivities and enantioselectivities in almost all cases.
About 4-Nitrobenzoic acid, If you have any questions, you can contact Rani, D; Bhargava, M; Agarwal, J or concate me.. Application In Synthesis of 4-Nitrobenzoic acid
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem