Safety of 4-Nitrobenzoic acid. I found the field of Chemistry very interesting. Saw the article Asymmetric Cycloaddition Reactions of Oxindole alpha-Keto Esters via Cascade Dienamine-Enamine and Trienamine Strategies published in 2019.0, Reprint Addresses Kesavan, V (corresponding author), Indian Inst Technol Madras, Chem Biol Lab, Dept Biotechnol, Bhupat & Jyothi Mehta Sch Biosci Bldg, Chennai 600036, Tamil Nadu, India.. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid.
An asymmetric [3 + 2] formal cycloaddition reaction between oxindole alpha-keto esters and enals has been developed. This alpha,gamma-regioselective reaction afforded multifunctional carbocyclic oxindoles via dienamine-enamine cascade reaction followed by isomerization. Furthermore, a highly enantioselective Diels-Alder reaction was demonstrated between 2,4-dienals and oxindole alpha-keto esters via trienamine intermediates. Chiral secondary amine catalyzed the both reactions under mild conditions and the cyclized products were isolated in moderate to good yields with good diastereoselectivities (>20:1 dr) and enantioselectivities (up to 99 %).
Safety of 4-Nitrobenzoic acid. About 4-Nitrobenzoic acid, If you have any questions, you can contact Muthusamy, S; Kesavan, V or concate me.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem