An article Rhodium-catalysed synthesis of fused pyrimidine derivatives employing N-sulfonyl-1,2,3-triazoles as a 1-aza-[4C] synthon WOS:000474321900010 published article about DIELS-ALDER REACTIONS; ALPHA,BETA-UNSATURATED IMINES; TANDEM REACTION; 1,2,3-TRIAZOLES; TRANSANNULATION; CYCLOADDITION; 2H-AZIRINES; ANNULATION; ALKYNES; 1-SULFONYL-1,2,3-TRIAZOLES in [Xu, Ze-Feng; An, Yuehui; Chen, Yidian; Duan, Shengguo] Zhejiang Sci Tech Univ, Dept Chem, Hangzhou 310018, Peoples R China; [Xu, Ze-Feng] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China in 2019, Cited 59. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. HPLC of Formula: C7H5NO4
A new synthetic application of N-sulfonyl-1,2,3-triazoles acting as a 1-aza-[4C] synthon via the 1,2-shift reaction of an alpha-imine rhodium carbene was developed for the synthesis of fused pyrimidine derivatives. The high reactivity of the strained three-membered 2H-azirine ring facilitated the unusual cyclization of electron-deficient dienes with electron-deficient dienophiles. The compatibility was good with common functionalities tolerated. Excellent chemoselectivity was observed, and no reactions occurred between the rhodium carbene and 2H-azirine. The products could be converted into seven-membered multi-functionalized 1H-1,4-diazepine derivatives, illustrating the potential application of the protocol in medium-sized N-heterocycle synthesis. (C) 2019 Elsevier Ltd. All rights reserved.
About 4-Nitrobenzoic acid, If you have any questions, you can contact Xu, ZF; An, YH; Chen, YD; Duan, SG or concate me.. HPLC of Formula: C7H5NO4
Reference:
Phthalazine – Wikipedia,
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