Month: October 2021

Application In Synthesis of 4-Nitrobenzoic acid. I found the field of Chemistry very interesting. Saw the article Asymmetric Michael Addition of Unactivated Ketones with beta-Nitrostyrenes Mediated by Bifunctional L-Prolinamide Organocatalysts published in 2020.0, Reprint Addresses Agarwal, J (corresponding author), Panjab Univ, Dept Chem, Chandigarh 160014, India.; Agarwal, J (corresponding author), Panjab Univ, Ctr Adv Studies, Chandigarh 160014, India.. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid.

The catalytic activity of two types of L-prolinamide organocatalysts was investigated for asymmetric Michael addition reaction of cyclic/acyclic ketones with beta-nitrostyrens. L-Prolinamides bearing amino groups on phenyl ring worked well, though their catalytic efficiency as well as selectivity was found to be dependent upon the position of amine group to the amide bond. Organocatalyst having -NH2 group ortho to amide bond provided the best results. Substrate scope was also studied by performing the reaction of various beta-nitrostyrenes with ketones to afford the corresponding Michael adducts in excellent yields with very high diastereoselectivities and enantioselectivities in almost all cases.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Rani, D; Bhargava, M; Agarwal, J or concate me.. Application In Synthesis of 4-Nitrobenzoic acid

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

In 2019.0 J MATER CHEM A published article about METAL NANOPARTICLE CATALYSTS; CHEMISTRY; NANOCLUSTERS; SUBSTRATE; CLUSTERS; RAMAN in [Yang, Liang-Liang; Wang, Hong-Juan; Wang, Juan; Li, Yu; Zhang, Wen; Lu, Tong-Bu] Tianjin Univ Technol, Sch Mat Sci & Engn, Inst New Energy Mat & Low Carbon Technol, Tianjin 300384, Peoples R China; [Lu, Tong-Bu] Sun Yat Sen Univ, Sch Chem, MOE Key Lab Bioinorgan & Synthet Chem, Guangzhou 510275, Guangdong, Peoples R China in 2019.0, Cited 53.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. Category: phthalazines

The development of sub-nanometric metal particles (<1 nm) as advanced heterogeneous catalysts has received considerable interest due to their outstanding catalytic performance, while the synthesis and stabilization of sub-nanometric catalysts (SNCs) without using additional surface capping agents remains a challenge. Herein, we report the synthesis of novel three-dimensional pyrenyl graphdiyne (Pyr-GDY) ultrafine nanofibers (3-10 nm), which can serve as an ideal substrate for electroless deposition and stabilization of Pd SNCs through the terminal uncoupled acetenyl groups in Pyr-GDY, with an average Pd particle size of only 0.83 nm. The as-synthesized Pd/Pyr-GDY composite shows extremely high catalytic activities for the reduction of nitroarenes to arylamines and Suzuki coupling reactions, 300 and 25 times higher than those of commercial Pd/C, respectively. The outstanding catalytic performance can be ascribed to the sub-nanometric Pd particles with a clean surface, and the unique three-dimensional network structure of Pyr-GDY, being favorable for rapid mass transfer. Our result provides an ideal carbon material for electroless deposition and stabilization of other SNCs with a clean surface, which will display outstanding catalytic activity for various catalytic reactions. About 4-Nitrobenzoic acid, If you have any questions, you can contact Yang, LL; Wang, HJ; Wang, J; Li, Y; Zhang, W; Lu, TB or concate me.. Category: phthalazines

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Pradhan, S; Roy, S; Banerjee, S; De, PB; Punniyamurthy, T in [Pradhan, Sourav; Roy, Subhasish; Banerjee, Sonbidya; De, Pinaki Bhusan; Punniyamurthy, Tharmalingam] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, India published Oxidative C-H/N-H Annulation of Aromatic Amides with Dialkyl Malonates: Access to Isoindolinones and Dihydrobenzoindoles in 2020.0, Cited 60.0. Product Details of 62-23-7. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7.

A copper-mediated oxidative C-H/N-H annulation of aromatic amides with dialkyl malonates has been presented to afford synthetically valuable dihydrobenzoindoles and isoindolinones. The reaction proceeds through direct oxidative C(sp(2))H/C(sp(3))-H coupling followed by an intramolecular N-H/C(sp(3))-H dehydrogenative coupling to deliver the target motifs with broad scope and functional group tolerance.

Product Details of 62-23-7. About 4-Nitrobenzoic acid, If you have any questions, you can contact Pradhan, S; Roy, S; Banerjee, S; De, PB; Punniyamurthy, T or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

In 2019 MOL CATAL published article about OXIDE GAS SENSORS; SOLVENT-FREE; ENERGY-CONVERSION; O-SILYLATION; SELECTIVE SILYLATION; METAL-OXIDES; ALCOHOLS; HMDS; PHENOLS; MILD in [Anbu, Nagaraj; Vijayan, Chellappa; Dhakshinamoorthy, Amarajothi] Madurai Kamaraj Univ, Sch Chem, Madurai 625021, Tamil Nadu, India in 2019, Cited 51. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. Recommanded Product: 62-23-7

In this study, a mild and efficient method is developed for the silylation of diverse functional groups using CeO2 nanoparticles (n-CeO2) as solid catalysts with hexamethyldisilazane (HMDS) as silylating agent at room temperature. Alcohols, phenols and acids are silylated to their respective silyl derivatives with faster reaction rate while amines and thiols required relatively longer reaction time. Moreover, the solid catalyst is easily be separated from the reaction mixture and recycled more than five times without any obvious decay in its activity. Powder X-ray diffraction (XRD), transmission electron microscope (TEM), UV-vis diffuse reflectance spectra (UV-DRS) and Raman analyses revealed identical structural integrity, particle size, absorption edge and valence state for the reused solid compared to the fresh solid catalyst.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Anbu, N; Vijayan, C; Dhakshinamoorthy, A or concate me.. Recommanded Product: 62-23-7

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Formula: C7H5NO4. I found the field of Chemistry; Materials Science very interesting. Saw the article Synthesis and Characterization of Hybrid Glycolipids as Functional Organogelators and Hydrogelators published in 2019.0, Reprint Addresses Wang, GJ (corresponding author), Old Dominion Univ, Dept Chem & Biochem, Norfolk, VA 23529 USA.. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid.

Carbohydrate-based low-molecular-weight gelators are useful and versatile compounds for the preparation of soft materials. Using N-acetyl-D-glucosamine as the starting material, we synthesized and characterized 15 glycolipids containing an amide with different ester functional groups. These include aliphatic derivatives with varying chain lengths and aromatic derivatives. Most of the hybrid amide-esters have molecular weights less than 500 D. These glycolipids were found to be effective gelators for several organic solvents, water, and aqueous solutions. Two efficient hydrogelators were also obtained at low concentrations. A few representative gels were characterized using optical microscopy, atomic force microscopy, and rheology to obtain information on their morphology and gel stability. Three gelators were also used to encapsulate naproxen sodium and toluidine blue. The sustained release of the drug from the gel to the aqueous phase was monitored by UV-vis spectroscopy. These gelators have structural flexibility that can be stimuli responsive. The esters can be hydrolyzed and several gels were converted to solutions under basic conditions. These rationally designed gelators could be utilized as stimuli-responsive smart materials with controlled release properties.

Formula: C7H5NO4. About 4-Nitrobenzoic acid, If you have any questions, you can contact Morris, J; Kozlowski, P; Wang, GJ or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

An article Asymmetric Diels-Alder reaction of 3-(acyloxy)acryloyl oxazolidinones: optically active synthesis of a high-affinity ligand for potent HIV-1 protease inhibitors WOS:000503782700038 published article about CYCLOADDITION REACTIONS; ENANTIOSELECTIVE CYCLOADDITION; CATALYSTS; BACKBONE; DESIGN in [Ghosh, Arun K.; Grillo, Alessandro; Kovela, Satish; Brindisi, Margherita] Purdue Univ, Dept Chem, 560 Oval Dr, W Lafayette, IN 47907 USA; [Ghosh, Arun K.] Purdue Univ, Dept Med Chem & Mol Pharmacol, 560 Oval Dr, W Lafayette, IN 47907 USA; [Brindisi, Margherita] Univ Naples Federico II, Dept Excellence Pharm, Naples, Italy in 2019.0, Cited 29.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. Name: 4-Nitrobenzoic acid

We describe here our investigation of the asymmetric Diels-Alder reaction of chiral 3-(acyloxy)acryloyl oxazolidinones as dienophiles in various Lewis-acid promoted reactions with cyclopentadiene. The resulting highly functionalized cycloadducts are useful intermediates for the synthesis, particularly for the optically active synthesis of 6-5-5 tricyclic hexahydro-4H-3,5-methanofuro[2,3-b]pyranol (3) with five contiguous chiral centers. This stereochemically defined crown-like heterocyclic derivative is an important high affinity ligand for a variety of highly potent HIV-1 protease inhibitors. Among the various dienophiles and Lewis acid-mediated reactions surveyed, 3-(4-methoxybenzoyl)acryloyl oxazolidinone as the dienophile and diethylaluminum chloride as the Lewis-acid provided the desired endo product with excellent diastereoselectivity. The cycloaddition was carried out in multi-gram scale and the cycloadduct was efficiently converted to alcohol 3 with high enantiomeric purity. The optically active ligand was then transformed into potent HIV-1 protease inhibitor 2.

Name: 4-Nitrobenzoic acid. About 4-Nitrobenzoic acid, If you have any questions, you can contact Ghosh, AK; Grillo, A; Kovela, S; Brindisi, M or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Retention of acidic and basic analytes in reversed phase column using fluorinated and novel eluent additives for liquid chromatography-tandem mass spectrometry published in 2020.0. HPLC of Formula: C7H5NO4, Reprint Addresses Kipper, K (corresponding author), Univ Tartu, Inst Chem, 14a Ravila St, EE-50411 Tartu, Estonia.; Kipper, K (corresponding author), St Georges Univ London, Analyt Serv Int, Cranmer Terrace, London SW17 0RE, England.. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid

This research focuses on retention mechanisms in a LC column with C18 stationary phase when novel eluent additives (HFIP, HFTB and TFE as well as NFTB and perfluoropinacol) are used. The retention factors between novel eluent additives and conventional ones like ammonium acetate and ammonium bicarbonate at different eluent pH values were compared. A simple set of drug-like molecules, widely spread over different logP values, containing protonated and deprotonated acids and bases was selected for this investigation. HFIP, HFTB, NFTB and PP demonstrated strong influence on basic polar analytes in basic medium. These additives drastically increased retention. A decrease in retention was observed for acidic analytes when novel eluent additives were used. Additionally, for the first time, the absolute pH (pH(abs)) scale was used for expressing the mobile phase pH. (C) 2020 The Authors. Published by Elsevier B.V.

HPLC of Formula: C7H5NO4. About 4-Nitrobenzoic acid, If you have any questions, you can contact Veigure, R; Lossmann, K; Hecht, M; Parman, E; Born, R; Leito, I; Herodes, K; Kipper, K or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Authors Xu, YW; Xu, XZ; Wu, B; Gan, CL; Lin, XY; Wang, J; Ke, F in WILEY-V C H VERLAG GMBH published article about NONACTIVATED CARBOXYLIC-ACIDS; CHEMISTRY RESEARCH AREAS; DIRECT AMIDATION; ALPHA,BETA-UNSATURATED AMIDES; C-O; AMINES; SUBSTITUTION; PERSPECTIVE; GENERATION; AMINATION in [Xu, Yiwen; Xu, Xiuzhi; Wu, Bin; Gan, Chenling; Lin, Xiaoyan; Wang, Jin; Ke, Fang] Fujian Med Univ, Inst Mat Med, Sch Pharm, Fujian Prov Key Lab Nat Med Pharmacol, Fuzhou 350122, Peoples R China in 2020, Cited 77. Recommanded Product: 62-23-7. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7

A visible-light-catalyzed radical N-acylation of amines with carboxylic acids was achieved by means of eosin Y as the photocatalyst under aqueous medium without any transition-metal-based catalytic systems. The new method takes advantages of visible-light photocatalysis to generate the amides under mild conditions. A variety of amides have been synthesized in good to excellent yields. Moreover, the strategy was successfully applied in the preparation of paracetamol.

Recommanded Product: 62-23-7. About 4-Nitrobenzoic acid, If you have any questions, you can contact Xu, YW; Xu, XZ; Wu, B; Gan, CL; Lin, XY; Wang, J; Ke, F or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Recently I am researching about STEREOSELECTIVE-SYNTHESIS; CYTOTOXIC MACROLIDES; REGIOSELECTIVE-SYNTHESIS; STRUCTURAL ELUCIDATION; N-VINYLAMIDES; ENAMIDES; AMIDES; ISOMERIZATION; AMINO; CYCLIZATION, Saw an article supported by the JSPS KAKENHIMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) [JP15H05848, JP16K05719, JP18K19079, JP18H01977, JP19K05455]; Frontier Research Base for Global Young Researchers, Osaka University, of the MEXT program; Mitsui Chemicals Award in Synthetic Organic Chemistry; Shorai Foundation for Science and Technology. Category: phthalazines. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Suzuki, K; Nishimoto, Y; Yasuda, M. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid

The reaction of alpha-(carbonylamino)allylic stannanes and alkyl halides using Et3B as a radical initiator selectively afforded (E)-enamides. A radical mechanism enables the E selectivity, which is unusual in a reaction using alpha-aminoallylic metals. In addition, this reaction system achieved a wide degree of functional group tolerance and an efficient chiral transfer reaction.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Suzuki, K; Nishimoto, Y; Yasuda, M or concate me.. Category: phthalazines

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Ghosh, S; Banerjee, J; Ghosh, R; Chattopadhyay, SK in [Ghosh, Subhankar; Banerjee, Jeet; Ghosh, Rajat; Chattopadhyay, Shital K.] Univ Kalyani, Dept Chem, Kalyani 741235, W Bengal, India published A metal-free iodine-mediated conversion of hydroxamates to esters in 2020, Cited 38. Product Details of 62-23-7. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7.

A metal-, oxidant-, and additive-free conversion of hydroxamates to esters have been achieved using molecular iodine as the reagent using a novel but not-so-explored heron-type rearrangement. The reaction proceeds with almost equal facility with substrates having either electron-donating or electron-withdrawing substituent. Similarly, alpha,ss-unsaturated, and sterically hindered ortho-substituted hydroxamates also undergo the desired transformation smoothly.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Ghosh, S; Banerjee, J; Ghosh, R; Chattopadhyay, SK or concate me.. Product Details of 62-23-7

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem