Recently I am researching about INFLUENZA-A; INHIBITORS; DISCOVERY, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81703366]; National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China [2019ZX09201001-003]; Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences [2016-I2M-1-011, 2016-I2M-3-014, 2017-I2M-3-019]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Wang, MH; Zhang, GN; Wang, YJ; Wang, JX; Zhu, M; Cen, S; Wang, YC. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid. Name: 4-Nitrobenzoic acid
Four 2,4-disubstituted quinazoline series containing various amide moieties were designed and synthesized as new anti-influenza A virus agents using the strategies of bio-isosterism and scaffold hopping. Many of them exhibit potent in vitro anti-influenza A virus activity and low cytotoxicity (CC50: > 100 mu M). Particularly, compounds 10a5 and 17a show better activity (IC50: 3.70-4.19 mu M) and higher selective index (SI: > 27.03, > 23.87, respectively) against influenza A/WSN/33 virus (H1N1), opening a new direction for quinazoline derivatives in anti-influenza A virus field.
Name: 4-Nitrobenzoic acid. Bye, fridends, I hope you can learn more about C7H5NO4, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem