Get Up to Speed Quickly on Emerging Topics:4-Nitrobenzoic acid

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Recently I am researching about FLUORINE; ACTIVATION; ARENES; TRIFLUOROETHYLATION; PHARMACEUTICALS; HETEROARENES, Saw an article supported by the Research Project of the Natural Science Foundation of Heilongjiang Province of China [B2018012]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Liu, XC; Mao, GJ; Qiao, JY; Xu, CZ; Liu, H; Ma, JJ; Sun, ZZ; Chu, WY. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid. HPLC of Formula: C7H5NO4

A Ni(TFA)(2)-catalyzed ortho-trifluoromethylation of 8-aminoquinoline derivatives was developed by acyl-directed C-H functionalization. A series of 7-trifluoromethylquinolinamine derivatives were originally obtained with moderate to excellent yields by using TMSCF3 as the trifluoromethylation reagent under mild conditions. In addition, the reaction mechanism is proposed and proved by the related experiment.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem