Computed Properties of C7H5NO4. In 2020 APPL ORGANOMET CHEM published article about DIRECT AMIDE FORMATION; BOND FORMATION; CONDENSATION in [Wang, Hui; Dong, Wei; Hou, Zhipeng; Cheng, Lidan; Li, Xiufen; Huang, Longjiang] Qingdao Univ Sci & Technol, Coll Chem Engn, State Key Lab Base Ecochem Engn, Qingdao 266042, Peoples R China in 2020, Cited 40. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7.
This paper described a mild and efficient direct amidation of non-activated carboxylic acid and amine derivatives catalyzed by TiCp2Cl2. Arylacetic acid derivatives reacted with different amines to afford the corresponding amides in good to excellent yield except of aniline. Aryl formic acids failed to react with aniline but smoothly reacted with aliphatic amines and benzylamine in moderate to good yield, fatty acids reacting with benzyl and aliphatic amines give amides in good to excellent yield. Chiral amino acids derivatives were transformed into amides without racemization in moderate yield. The possible mechanism of direct amidation catalyzed by TiCp2Cl2 was discussed. This catalytic method is very suitable for the amidation of low sterically hindered arylacetic acid, fatty acids with different low sterically hindered amines except aniline, as well as the amidation of aryl formic acid with benzyl and aliphatic amines.
Computed Properties of C7H5NO4. Welcome to talk about 62-23-7, If you have any questions, you can contact Wang, H; Dong, W; Hou, ZP; Cheng, LD; Li, XF; Huang, LJ or send Email.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem