Application In Synthesis of 4-Nitrobenzoic acid. Shinohara, R; Morita, M; Ogawa, N; Kobayashi, Y in [Shinohara, Riku; Morita, Masao; Kobayashi, Yuichi] Tokyo Inst Technol, Dept Bioengn, Midori Ku, Box B-52,Nagatsuta Cho 4259, Yokohama, Kanagawa 2268501, Japan; [Ogawa, Narihito] Meiji Univ, Dept Appl Chem, Tama Ku, 1-1-1 Higashimita, Kawasaki, Kanagawa 2148571, Japan published Use of the 2-Pyridinesulfonyloxy Leaving Group for the Fast Copper-Catalyzed Coupling Reaction at Secondary Alkyl Carbons with Grignard Reagents in 2019, Cited 44. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7.
Investigation of the copper-catalyzed coupling reaction of 2-pyridinesulfonates with Grignard reagents revealed that reactions with catalytic Cu(OTf)(2) were completed in <40 min. The results differed from those of the previous CuI-catalyzed reactions of tosylates in the presence of additives (LiOMe and TMEDA) for 12-24 h. It was shown that the preferred coordination of the leaving group to the reagents accelerated the reaction. Successful reagents were MeMgCl and other RMgX. Complete inversion was established. Welcome to talk about 62-23-7, If you have any questions, you can contact Shinohara, R; Morita, M; Ogawa, N; Kobayashi, Y or send Email.. Application In Synthesis of 4-Nitrobenzoic acid
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