Recently I am researching about II NADH DEHYDROGENASE; DERIVATIVES; OXIDOREDUCTASE; ACTIVATION; INHIBITORS; SERIES, Saw an article supported by the Maurice Wilkins Centre for Molecular Biodiscovery. Computed Properties of C7H5NO4. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Santoso, KT; Brett, MW; Cheung, CY; Cook, GM; Stocker, BL; Timmer, MSM. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid
Drug-resistant strains of Mycobacterium tuberculosis are on the rise and have resulted in an urgent need to develop new tuberculosis (TB) drugs. Herein, the development of chromonyl-pyrimidines as a new TB drug scaffold is presented. A library of eleven chromonyl-pyrimidines was synthesised, from which lead compound 6-((2-amino-6-methylpyrimidin-4-yl)amino)-3-benzoyl-2-phenyl-4H-chromen-4-one (MIC=36 mu M against M. tuberculosis) was identified. A second-generation library of seven aryl-substituted chromonyl-pyrimidines was then prepared, with six chromonyl-pyrimidines exhibiting an improved M. tuberculosis growth inhibition (MIC=12.5 mu M). From this work, the potential of chromonyl-pyrimidines as therapeutics for TB is demonstrated.
Bye, fridends, I hope you can learn more about C7H5NO4, If you have any questions, you can browse other blog as well. See you lster.. Computed Properties of C7H5NO4
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem