Formula: C7H5NO4. Wang, MH; Zhang, GN; Wang, YJ; Wang, JX; Zhu, M; Cen, S; Wang, YC in [Wang, Minghua; Zhang, Guoning; Wang, Yujia; Wang, Juxian; Zhu, Mei; Cen, Shan; Wang, Yucheng] Chinese Acad Med Sci & Peking Union Med Coll, Inst Med Biotechnol, Beijing 100050, Peoples R China published Design, synthesis and anti-influenza A virus activity of novel 2,4-disubstituted quinazoline derivatives in 2020, Cited 28. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7.
Four 2,4-disubstituted quinazoline series containing various amide moieties were designed and synthesized as new anti-influenza A virus agents using the strategies of bio-isosterism and scaffold hopping. Many of them exhibit potent in vitro anti-influenza A virus activity and low cytotoxicity (CC50: > 100 mu M). Particularly, compounds 10a5 and 17a show better activity (IC50: 3.70-4.19 mu M) and higher selective index (SI: > 27.03, > 23.87, respectively) against influenza A/WSN/33 virus (H1N1), opening a new direction for quinazoline derivatives in anti-influenza A virus field.
Formula: C7H5NO4. Bye, fridends, I hope you can learn more about C7H5NO4, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem