Brief introduction of 4-Nitrobenzoic acid

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I found the field of Chemistry very interesting. Saw the article Organocatalytic Asymmetric Domino Oxa-Michael-Mannich-[1,3]-Amino Rearrangement Reaction of N-Tosylsalicylimines to alpha,beta-Unsaturated Aldehydes by Diarylprolinol Silyl Ethers published in 2020.0. Computed Properties of C7H5NO4, Reprint Addresses Chen, F (corresponding author), Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China.; Chen, F (corresponding author), Zhejiang Univ Technol, Inst Pharmaceut Sci & Technol, 18 Chao Wang Rd, Hangzhou 310014, Peoples R China.. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid

An organocatalytic asymmetric enantioselective domino oxa-Michael-Mannich-[1,3]-amino rearrangement reaction of N-tosylsalicylimines with a wide range of alpha,beta-unsaturated aldehydes utilizing diarylprolinol silyl ether catalysis is described. The catalytic reactions proceed with excellent enantioselectivity (up to 99% ee) to produce the corresponding chair N-tosylimines-chromenes with a yield of up to 99%, tolerating a range of functional groups. This methodology offers a new method with great potential to further extend the synthetic power and versatility of chiral aminocatalysis.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem