Application In Synthesis of 4-Nitrobenzoic acid. I found the field of Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Discovery of novel phenoxybenzamide analogues as Raf/HDAC dual inhibitors published in 2019.0, Reprint Addresses Zhu, Y (corresponding author), China Pharmaceut Univ, Sch Sci, Dept Organ Chem, 639 Longmian Ave, Nanjing 211198, Jiangsu, Peoples R China.; Lu, T (corresponding author), China Pharmaceut Univ, Sch Sci, Lab Mol Design & Drug Discovery, 639 Longmian Ave, Nanjing 211198, Jiangsu, Peoples R China.. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid.
Histone deacetylase (HDAC) inhibitors as an important epigenetic therapeutic strategy affect signaling networks and act synergistically with kinase inhibitors for the treatment of cancer. Herein we presented a series of novel phenoxybenzamide analogues with inhibition of Raf and HDAC. Among them, compound 10e showed potent antiproliferative activities against Hepg2 and MDA-MB-468 in cellular assays. This work may lay the foundation for developing novel dual Raf/HDAC inhibitors as potential anticancer therapeutics.
Application In Synthesis of 4-Nitrobenzoic acid. Welcome to talk about 62-23-7, If you have any questions, you can contact Geng, AX; Cui, H; Zhang, LY; Chen, X; Li, HM; Lu, T; Zhu, Y or send Email.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem