Authors Liang, DL; Fan, YZ; Yang, Z; Zhang, ZG; Liu, MY; Liu, L; Jiang, C in ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER published article about ACETALDEHYDE; ADDUCTS; DNA in [Liang, Dailin; Yang, Zhou; Zhang, Zhenguo; Jiang, Cheng] China Pharmaceut Univ, Jiang Su Key Lab Drug Design & Optimizat, Tongjiaxiang 24, Nanjing 210009, Peoples R China; [Liang, Dailin; Yang, Zhou; Zhang, Zhenguo; Liu, Meiyang; Jiang, Cheng] China Pharmaceut Univ, Dept Med Chem, Tongjiaxiang 24, Nanjing 210009, Peoples R China; [Fan, Yazhou; Liu, Li] China Pharmaceut Univ, Key Lab Drug Metab & Pharmacokinet, Tongjiaxiang 24, Nanjing 210009, Peoples R China in 2020.0, Cited 26.0. Computed Properties of C7H5NO4. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7
Overexpression of aldehyde dehydrogenase 1A1 (ALDH1A1) is associated with the occurrence and development of obesity and insulin resistance. Herein, a series of coumarin-based ALDH1A1 inhibitors were designed, synthesized and evaluated. Among them, compounds 10, 14 and 26 exhibited potent inhibitory activity against ALDH1A1 and high selectivity over ALDH1A2, ALDH1A3, ALDH2 and ALDH3A1. Optimized compound 10 showed markedly improved pharmacokinetic characters and ADME profiles comparing to the lead compound 1. In vitro study demonstrated that 10 alleviated palmitic acid-induced impairment of glucose consumption in HepG2 cells. (C) 2019 Elsevier Masson SAS. All rights reserved.
Welcome to talk about 62-23-7, If you have any questions, you can contact Liang, DL; Fan, YZ; Yang, Z; Zhang, ZG; Liu, MY; Liu, L; Jiang, C or send Email.. Computed Properties of C7H5NO4
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Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem