HPLC of Formula: C7H5NO4. Patel, H; Jadhav, H; Ansari, I; Pawara, R; Surana, S in [Patel, Harun; Jadhav, Harsha; Ansari, Iqrar; Pawara, Rahul; Surana, Sanjay] RC Patel Inst Pharmaceut Educ & Res, Dept Pharmaceut Chem, Shirpur, India published Pyridine and nitro-phenyl linked 1,3,4-thiadiazoles as MDR-TB inhibitors in 2019, Cited 33. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7.
In the present study, a series of substituted 1,3,4-thiadiazole derivatives 4(a-o), 5(a-m) and 6(a-j) were synthesized and characterized by IR, H-1 NMR, C-13 NMR and mass spectroscopic technique. The synthesized compounds were evaluated for their in vitro anti-mycobacterial activity against the Mycobacterium tuberculosis H37Rv and resistance MDR-TB strain. Among the compounds tested N-(5-(4-nitrophenyl)-1,3,4-thiadiazol-2-yl)furan-2-carboxamide (4h) showed significant inhibitory activity with MIC of 9.87 mu M (H37Rv strain) and 9.87 mu M (MDR-TB strain) compared to isoniazide (MIC of 3.64 mu M (H37Rv) and >200 mu M (MDR-TB strain)] and rifampin [MIC of 0.152 mu M (H37Rv) and 128 mu M (MDR-TB strain)]. In addition, these compounds have also been assessed for their cyto-toxicity to a mammalian Vero cell line using the MTT assay. The result shows that these compounds exhibit anti-tubercular activity at non-cytototoxic concentrations. (C) 2019 Elsevier Masson SAS. All rights reserved.
HPLC of Formula: C7H5NO4. Bye, fridends, I hope you can learn more about C7H5NO4, If you have any questions, you can browse other blog as well. See you lster.
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Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem