SDS of cas: 62-23-7. Recently I am researching about BORDETELLA-PERTUSSIS; CARBOHYDRATE; GLYCOSYLATION; ANTIBODIES; INDUCTION; EVOLUTION; INFECTION; BETA; CELL, Saw an article supported by the National Institute of Allergy and Infectious Diseases, NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of Allergy & Infectious Diseases (NIAID) [R01AI146210, R01AI125560]; National Cancer Institute, NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Cancer Institute (NCI) [R01CA225105]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Wang, P; Huo, CX; Lang, SY; Caution, K; Nick, ST; Dubey, P; Deora, R; Huang, XF. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid
With the infection rate of Bordetella pertussis at a 60-year high, there is an urgent need for new anti-pertussis vaccines. The lipopolysaccharide (LPS) of B. pertussis is an attractive antigen for vaccine development. With the presence of multiple rare sugars and unusual glycosyl linkages, the B. pertussis LPS is a highly challenging synthetic target. In this work, aided by molecular dynamics simulation and modeling, a pertussis-LPS-like pentasaccharide was chemically synthesized for the first time. The pentasaccharide was conjugated with a powerful carrier, bacteriophage Q beta, as a vaccine candidate. Immunization of mice with the conjugate induced robust anti-glycan IgG responses with IgG titers reaching several million enzyme-linked immunosorbent assay (ELISA) units. The antibodies generated were long lasting and boostable and could recognize multiple clinical strains of B. pertussis, highlighting the potential of Q beta-glycan as a new anti-pertussis vaccine.
Welcome to talk about 62-23-7, If you have any questions, you can contact Wang, P; Huo, CX; Lang, SY; Caution, K; Nick, ST; Dubey, P; Deora, R; Huang, XF or send Email.. SDS of cas: 62-23-7
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem