Synthetic Route of 253-52-1, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.253-52-1, Name is Phthalazine, molecular formula is C8H6N2. In a Article£¬once mentioned of 253-52-1
A modular synthesis of polysubstituted indolizines
The N-alkylation of pyridines with cyanohydrin triflates or alpha-halonitriles furnishes 1-(1-cyanoalkyl)pyridinium salts that can react with nitroolefins under basic conditions to furnish polysubstituted indolizines. Overall, the indolizine core can be constructed from a pyridine, two aldehydes, and a nitroalkane, and no undesired functional groups remain in the products. When bromoacetonitrile was used for the N-alkylation, indolizine-3-carbonitriles were obtained instead. The pyridine component may be replaced by other azines, giving rise to related heterocyclic systems. Polysubstituted indolizines were synthesized through [3+2] cycloaddition of nitroalkenes with pyridinium ylides. In contrast to previous reports of 1,3-dipolar cycloadditions, in this work no electron-deficient groups remain in the products. Copyright
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 253-52-1, and how the biochemistry of the body works.Synthetic Route of 253-52-1
Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N242 – PubChem