The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.Phthalazin-1(2H)-one, cas is 119-39-1,the phthalazine compound. A new synthetic method of this compound is introduced below. 119-39-1
Stage A 2-{2-[(Tetrahydro-2-pyranyl)oxy]ethyl}-1-oxophthalazine A solution of 41.5 g of potassium hydroxide in 53 ml of water is added at room temperature to a solution of 61 g of 1-oxophthalazine in 430 ml of dimethyl sulfoxide. After 30 minutes, 130 g of tetrahydro-2-pyranyl 2-bromoethyl ether are added to the suspension obtained. The mixture is left stirring for 30 hours at room temperature and then concentrated, the residue is taken up in 400 ml of water and the product is extracted with dichloromethane. The organic phase is concentrated. Yield: 80% Proton nuclear magnetic resonance spectrum (400 MHz, solvent CDCl3): 1.3 to 2 ppm,m,6H; 3.3 to 4.8 ppm,m+m, 1H+6H; 7.6 to 7.9 ppm,m,3H; 8.15 ppm,s,1H; 8.4 ppm,m,1H
119-39-1, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,119-39-1 ,Phthalazin-1(2H)-one, other downstream synthetic routes, hurry up and to see
Reference£º
Patent; Adir et Compagnie; US5077288; (1991); A;,
Phthalazine – Wikipedia
Phthalazine | C8H6N2 – PubChem