In an article, author is Wang, Shi-Ben, once mentioned the application of 622-95-7, Safety of 1-(Bromomethyl)-4-chlorobenzene, Name is 1-(Bromomethyl)-4-chlorobenzene, molecular formula is C7H6BrCl, molecular weight is 205.4795, MDL number is MFCD00040714, category is phthalazines. Now introduce a scientific discovery about this category.
Synthesis and Anticonvulsant Activity Evaluation of Some 1-alkoxy-4-(1H-1,2,4-triazol-1-yl)phthalazines
A series of 1-alkoxy-4-(1H-1,2,4-triazol-1-yl)phthalazine derivatives were synthesized using 2,3-dihydrophthalazine-1,4-dione as starting material. The structures of the compounds were characterized by elemental analysis, IR, H-1-NMR and MS data. Anticonvulsant activities of these compounds were evaluated by maximal electroshock (MES) test following intraperitoneal injection in mice. Among the synthesized compounds 3a-3t, compound 3e was the most active compound with an ED50 of 28.9 mg/kg, TD50 of 173.6 mg/kg and protective index (PI) of 6.0.
If you are interested in 622-95-7, you can contact me at any time and look forward to more communication. Safety of 1-(Bromomethyl)-4-chlorobenzene.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem